Haifei Shi

Haifei Shi

Associate Professor

318 Hughes Hall

Biographical Information

Obesity is a major health problem exacerbating many other disorders and is a health risk in its own right. Our research focuses on the neural and hormonal control of energy metabolism, and the mechanisms of pathological conditions of obesity and related diseases including cancer. Males and females adopt fundamentally different strategies to maintain energy balance. This is an important issue for understanding and treating obesity and related disorders, which has not received enough scientific attention. The overall research goal is to investigate effects of sex hormones in the regulation of energy metabolism. Graduate and undergraduate students in my laboratory use physiological, biochemical, and molecular techniques in their projects.

Courses Taught

  • Human physiology (BIO 305)
  • Endocrinology (BIO 454/554)
  • Undergraduate seminar (BIO 490)
  • Graduate seminar (BIO 710)
  • Independent study (BIO 177, 277, 320, 340, 377, 620, etc)

Recent Publications

  • Krolick KN, Zhu Q, Shi H. Effects of estrogen on central nervous system neurotransmission: implication for sex differences in mental disorders. Prog Mol Biol Transl Sci. 160: In press.
  • Shen M, Cao J, Shi H. Effects of estrogen and estrogen receptors on transcriptomes of HepG2 cells. Int J Endocrinol. In press.
  • Cao J, Zhu Q, Liu L, Glazier BJ, Hinkel BC, Liang C, Shi H (2018). Global transcriptome analysis of brown adipose tissue of diet-induced obese mice. Int J Mol Sci. 19(4). doi: 10.3390/ijms19041095.
  • Kalyani M, Callahan P, Janik JM, Shi H (2017). Effects of pup separation on stress response in postpartum female rats.Int J Mol Sci. 18(7). pii: E1370. doi: 10.3390/ijms18071370.
  • Kalyani M, Hasselfeld K, Janik JM, Callahan P, Shi H (2016).Effects of high-fat diet on stress response in male and female wildtype and prolactin knockout mice.PLoS One. 11(11):e0166416. doi: 10.1371/journal.pone.0166416.
  • Shen M, Shi H (2016).Estradiol and estrogen receptor agonists oppose oncogenic actions of leptin in HepG2 cells.PLoS One. 11(3):e0151455. doi: 10.1371/journal.pone.0151455.