Anna Radke

Radke Fall 2016

Associate Professor

112 Psychology Building
Oxford, OH 45056
513-529-6941
aradke@MiamiOH.edu

I am trained as a behavioral neuroscientist and my research focuses on motivational brain systems. My lab uses mouse models of behavior to study positive and negative motivational states, specifically as they relate to psychiatric disorders and addiction. I earned a BA in Biology from St. Olaf College and a PhD in Neuroscience from the University of Minnesota. Prior to joining the faculty at Miami in 2016, I completed a postdoctoral fellowship at the National Institute on Alcohol Abuse and Alcoholism. I have a strong interest in mentoring undergraduate and graduate students in research.

Education

  • Postdoctoral Fellowship, National Institutes of Health 2012-2016
  • PhD, University of Minnesota, 2011
  • BA, St. Olaf College, 2006

Teaching Interests

I teach Biopsychology and Neuroscience courses in the Psychology department. I enjoy exposing students to the workings of the brain and teaching students to be critical consumers of scientific information.

Research Interests

In the Reward and Addictive Disorders (RAD) Lab, we use animal models to study motivational brain circuits on a systems level. Our goal is to understand how these neural circuits function in a healthy state as well as to uncover adaptations that contribute to maladaptive behaviors such as addiction. Currently, we are investigating glutamatergic and dopaminergic contributions to punishment-resistant alcohol drinking as well as mechanisms contributing to sex differences in alcohol drinking behaviors. Our principle experimental approaches include manipulating behavior with pharmacological, genetic, and chemogenetic tools.

Professional Recognition

  • Psi Chi Psychology Professor of the Year (2022)
  • Alumni Teaching Scholar, Miami University (2019-2020)
  • Postdoctoral Mentor Award, National Institutes of Health (2013, 2014, 2015)

Selected Publications

  • Sneddon EA*, Schuh KM**, Frankel JW**, Radke AK. (2021). The contribution of medium spiny neuron subtypes in the nucleus accumbens core to compulsive-like alcohol drinking. Neuropharmacology 187: 108497.
  • Monroe SC* & Radke AK. (2021). Aversion-resistant fentanyl self-administration in mice. Psychopharmacology 238: 699-710.
  • Sneddon EA*, Ramsey OR**, Thomas AM**, Radke AK. (2020). Increased responding for alcohol and resistance to aversion in female mice. Alcoholism: Clinical and Experimental Research 44: 1400-1409.
  • Radke AK, Held IT**, Sneddon EA*, Riddle CA**, Quinn JJ. (2020). Additive influences of acute early life stress and sex on vulnerability for aversion-resistant alcohol drinking. Addiction Biology 25: e12829.
  • Sneddon EA*, White RD**, Radke AK. (2019). Sex differences in binge-like alcohol drinking and resistance to aversion in C57BL6/J mice. Alcoholism: Clinical and Experimental Research 43: 243-249.
  • Radke AK, Jury NJ, Kocharian AK, Marcinkiewcz CA, Lowery-Gionta EG, Pleil KE, McElligot ZA, McKlveen JM, Kash TL, Holmes A. (2017). Chronic EtOH effects on putative measures of compulsive behavior in mice. Addiction Biology 22:423-434.

*Miami graduate student  **Miami undergraduate student

View a complete list of publications

Grants

  • Miami University, Rapid Investment Program grant, Sex chromosome regulation of female vulnerability to alcohol drinking behaviors, $96,000, 2022-2023
  • R21 Exploratory/Developmental Research Grant, National Institute on Alcohol Abuse and Alcoholism, Sex-specific effects of infant trauma on alcohol drinking: Role of amygdala intercalated neurons, $367,893, 2021-2023 (PI)
  • F99 Predoctoral to Postdoctoral Fellow Transition Award, National Institute on Neurological Disorders and Stroke, Mechanisms underlying female vulnerability to compulsive alcohol drinking, $93,040, 2020-2022 (Sponsor; PI: Sneddon)
  • R15 Academic Research Enhancement Award, National Institute on Alcohol Abuse and Alcoholism, Analysis of subcortical networks that promote aversion-resistant alcohol drinking, $378,136, 2020-2023 (PI)
  • Miami University, Committee on Faculty Research grant, Defining the neural circuits responsible for opioid reward and aversion, $38,700, 2018-2019
  • Miami University, Office for the Advancement of Research and Scholarship grant, Preliminary data on the neurobiological mechanisms of opioid abuse, $15,270, 2018-2019
  • Miami University, College of Arts and Sciences, Do dopamine neurons contribute to compulsive alcohol-drinking?, $5,000, 2017

Research Lab Information

Undergraduate students interested in joining the Reward and Addictive Disorders lab should fill out an application at www.aradlab.com/contact.

Interested graduate students should contact Dr. Radke directly.

RAD Lab

Dr. Radke leads the Reward and Addictive Disorders Lab

Learn more about the RAD Lab